Site: The Brigham and Women's Hospital, Inc.

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The Research Assistant works within the clinical research program and supports the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator(s) and the DF/HCC Clinical Trials Office and/or MGB Institutional Review Board (IRB).
The Research Assistant (RA) will be responsible for the primary data collection and management of patient clinical information as it pertains to participation in clinical trials. We are looking for a highly organized candidate with great attention to detail for the position of data coordinator. RAs are responsible for data entry, cleaning, transformations, and data analyses as requested by analysts or senior management.
Additionally, RAs will need to adhere to legal and regulatory standards, among other duties, requiring them to maintain excellent organizational skills and data integrity. For this role, the Research Assistant will support work from a faculty member focused on application of artificial intelligence and data science to optimize the care of cancer patients with a focus on lung cancer. The faculty member(s) is committed to training and inspiring the next generation of health care leaders and clinicians, working on important clinical and healthcare issues, and utilizing new technologies like AI to improve outcomes and reduce toxicity. We seek an energetic and organized, and detail-oriented individual to assist with a portfolio of data science research projects in the Department of Radiation Oncology. Candidates with backgrounds in data science and informatics and/or experience with programming languages are preferred.
Because the team builds and maintains its own AI models, data pipelines, and research web applications in-house, this role combines clinical research coordination with hands-on data science and software engineering. Candidates who are comfortable working in a Linux environment, using version control, containerizing and deploying applications, and applying best SWE and Data Science practices are especially encouraged to apply. Prior exposure to clinical/healthcare data, electronic health records, and Good Clinical Practice (GCP) is an asset.

1. The successful candidate will be able to work with faculty and research team members to accomplish, data compilation, data management, statistical programming, and other research related duties.

2. May assist the study start-up process from receipt of protocols through the Scientific Review Committee and IRB submissions, and site activation activities

3. May assist coordinating and management of clinical trials, interact with study participants as directed/required by the protocol and/or study team.

4. These duties and responsibilities include but are not limited to, the following:

• Extracting data from electronic health records

• Management of a large lung cancer patient database including regulatory considerations

• Compiling and cleaning data from various sources as well as assessing the data quality; routine data maintenance

• Statistical programming on large data sets (For example: analyzing data sets extracted from electronic health record databases)

• Analysis and validation of empirical results

• Participating in manuscript presentations with opportunities for co-authorship

• Producing charts and tables for manuscripts and presentations

• Analyzing pilot data to support the start-up of new projects

• Onboarding new research collaborators

• Querying and harmonizing data across multiple clinical, imaging, and research systems (e.g., the electronic health record, research data registries, and radiation-oncology treatment-planning systems)

• Developing and maintaining reproducible, version-controlled data-science pipelines and analysis code (e.g., using Git/GitHub)

• Training, running, and validating deep-learning models on GPU infrastructure, including models applied to medical imaging and digital biomarkers

• Building, maintaining, and deploying research web applications across development, staging, and production environments

• Containerizing applications and supporting deployment and release workflows

• Maintaining clinical trial regulatory documentation and supporting protocol/staff onboarding and IRB submissions in accordance with Good Clinical Practice

• Other duties as assigned

5. Project topics include, but are not limited to:

• Impact of radiation therapy on cardiac function and cardiac complications

• Quantifying patient health/frailty from medical imaging using AI

• Deep learning-based analysis of thoracic CT imaging to predict survival outcomes

• Automation of radiation therapy planning and risk prediction with AI

• Quantification of biological age and health from facial photographs and other medical imaging using deep learning

• Development of large language model (LLM) and retrieval-augmented (RAG) tools for clinical research and knowledge management

• Building and maintaining web platforms for deploying AI biomarkers and supporting prospective data collection

Additional Job Details (if applicable)

Qualifications:

Education
Bachelor's Degree Science required
Can this role accept experience in lieu of a degree?
Yes
Experience
New grad with some relevant coursework 0-1 year preferred

• Careful attention to details
• Good organizational skills
• Must have working knowledge of Excel
• Must have working knowledge of SAS, Stata, Python, or R
• Must have working knowledge of statistical analysis and data science (running and interpreting regressions, data visualization)
• Demonstrated knowledge of and experience working with health care-related research
• Experience in quantitative research methods and analysis

Preferred Skills (Data Science & Software Engineering)

• Proficiency with Python for data analysis and machine learning (e.g., pandas, NumPy, scikit-learn)

• Experience with deep-learning frameworks (e.g., PyTorch or TensorFlow) and GPU-accelerated model training/inference

• Comfort working in a Linux/Unix environment and on remote servers via the command line (SSH)

• Experience with version control systems (Git / GitHub) for collaborative, reproducible code

• Experience with containerization (Docker) and deploying applications across development, staging, and production environments

• Experience building or maintaining web applications (e.g., Python web frameworks such as Streamlit, Flask, or Django; basic front-end familiarity)

• Working knowledge of SQL and relational databases

• Experience with electronic data capture and clinical research systems (e.g., REDCap) and with electronic health record / clinical data extraction

• Familiarity with medical imaging data (e.g., DICOM, CT)

• Familiarity with large language models (LLMs), retrieval-augmented generation (RAG), or other applied AI tooling

• Familiarity with cloud or high-performance computing environments

Hybrid

221 Longwood Avenue

40

Regular

Day (United States of America)

Pay Range

$21.00 - $29.01/Hourly

Grade

5

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

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